Obstetrics, Gynaecology and Reproductive Medicine
Volume 18, Issue 3 , Pages 69-75, March 2008

Hyperemesis gravidarum, gastrointestinal and liver disease in pregnancy

Nikos A Kametas MRCOG is a Subspecialty Trainee in Maternal and Fetal Medicine at King's College Hospital, London, UK

Catherine Nelson-Piercy FRCOG is a Consultant Obstetric Physician at St Thomas' Hospital & Queen Charlotte’s Hospital, London, UK

Abstract 

Up to 80% of pregnant women experience discomfort due to symptoms originating from the gastrointestinal tract; ∼5% of them have more severe disease that can adversely affect maternal and fetal outcome. This review presents options of symptomatic relief for the common complaints of the gastrointestinal tract. It also discusses the management of the commonest or most serious conditions of the gastrointestinal tract and liver that can coexist or appear for the first time in pregnancy.

Keywords: AFLP, coeliac disease, Crohn’s disease, HELLP, hepatitis, hyperemesis gravidarum, obstetric cholestasis, pregnancy, ulcerative colitis

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PII: S1751-7214(08)00004-3

doi:10.1016/j.ogrm.2008.01.003

Obstetrics, Gynaecology and Reproductive Medicine
Volume 18, Issue 3 , Pages 69-75, March 2008