Research Article| Volume 9, ISSUE 2, P62-68, June 1999

Pre-existing endocrine disease in relation to pregnancy

  • W.M. Hague
    W.M. Hague, MD(Cantab), MRCP(UK), FRCOG, Consultant Physician in Obstetric Medicine, Women's and Children's Hospital, North Adelaide Clinical Senior Lecturer, Department of Obstetrics, University of Adelaide, South Australia, Australia
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      This article reviews the impact of pre-existing endocrine disorders on pregnancy, including diabetes mellitus, hypo- and hyperthyroidism, adrenal and pituitary disorders, and hyper- and hypoparathyroidism. Pregnancy usually requires a state of endocrine balance, i.e. the chances of conception are reduced unless the endocrine milieu is normal. Many of the endocrine diseases will also affect the outcome of pregnancy, either directly or indirectly. Pregnancy in some of the disorders is relatively rare, so that management is often based on limited information and clinical judgement rather than on strong evidence-based criteria.
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