Research Article| Volume 9, ISSUE 2, P69-74, June 1999

Respiratory disease in pregnancy

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      Respiratory diseases are an important cause of morbidity and mortality in pregnant women. Chronic lung diseases, such as asthma and cystic fibrosis, may present unique management problems in pregnancy, and other lung diseases, such as pneumonia and tuberculosis, can target pregnant women just as they target non-pregnant women. Other disease such as pulmonary embolism may be made more likely owing to the pregnant state. In this review we will cover the important lung diseases that are likely to be encountered in pregnancy and highlight any modifications in conventional management which are necessary.
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        • ACOG technical bulletins
        Pulmonary disease in pregnancy.
        Int J Gynaecol Obstet. 1996; 54: 187-196
        • Dombrowski M.P.
        Pharmacological therapy of asthma during pregnancy.
        Obstet Gynaecol Clin N Amer. 1997; 24: 559-574
        • Schatz M.
        • Zeiger R.S.
        Asthma and allergy in pregnancy.
        Clin Perinatol. 1997; 24: 407-432
        • Witlin A.G.
        Asthma in pregnancy.
        Semin Perinatol. 1997; 21: 284-297
        • Schatz M.
        • Zeiger R.S.
        • Harden K.
        • Hoflman C.C.
        • Chilingar L.
        • Petitti D.
        The safety of asthma and allergic medications during pregnancy.
        J Allergy Clin Immunol. 1997; 100: 301-306
        • Schatz M.
        Asthma treatment during pregnancy.
        Drug Safety. 1997; 16: 342-350
      1. Thorax. 1997; 52 (suppl): s1-s21
        • Reiss T.F.
        • Hill J.B.
        • Harman E.
        • et al.
        Increased urinary and excretion of LTE4 after exercise and attenuation of exercise-induced bronchospasm by montelukast, a cysteinyl leukotriene receptor antagonist.
        Thorax. 1997; 52: 1030-1035
        • Krell R.D.
        • Dehass C.J.
        • Lengel D.J.
        • Kusner E.J.
        • Williams J.C.
        • Buckner C.R.
        Preclinical exploration of the potential anti-inflammatory properties of the peptide leukotriene antagonist. ICI 204, 219.
        Ann NY Acad Sci. 1994; 144: 289-298
        • Stenius-aarniala B.S.M.
        • Hedman J.
        • Teramo K.A.
        Acute asthma during pregnancy.
        Thorax. 1996; 51: 411-414
        • Wendel P.J.
        • Ramins M.
        • Barnett-Hamm C.
        • Rowe T.F.
        • Cunningham F.G.
        Asthma treatment in pregnancy: a randomised controlled study.
        Am J Obstet Gynaecol. 1996; 175: 150-154
        • Siegel B.
        • Siegel S.
        Pregnancy and delivery in a patient with cystic fibrosis of the pancreas: report of a case.
        Obstet Gynaecol. 1960; 16: 438-440
        • Cowen L.F.
        • Di Sant-Agnese P.A.
        • Friedlander J.
        Cystic fibrosis in pregnancy. A national survey.
        Lancet. 1980; : 842-844
        • Kotlof R.M.
        Reproductive issues in patients with cystic fibrosis.
        Semin Respire and Crit Care Med. 1994; 15: 402-413
        • Edenborough F.P.
        • Stableforth D.E.
        • Webb A.K.
        • Mackenzie W.E.
        • Smith D.L.
        Outcome of pregnancy in women with cystic fibrosis.
        Thorax. 1995; 50: 170-174
        • Olson G.L.
        Cystic Fibrosis in pregnancy.
        Semin Perinatol. 1997; 21: 307-312
        • Hilman B.C.
        • Aitken M.
        • Constantinesen M.
        Pregnancy in patients with cystic fibrosis.
        Clin Obstet Gynaecol. 1997; 39: 70-86
        • Toglia M.R.
        • Nolan T.E.
        Venous thrombo embolism during pregnancy. A current review of diagnostic management.
        Obstet Gynaecol Surv. 1996; 52: 60-72
        • Bates S.M.
        • Ginsberg J.S.
        Thrombosis in pregnancy.
        Current opinion in Haematology. 1997; 4: 335-343
        • British Thoracic Society Standards of Care Committee
        Suspected pulmonary embolism: a practical approach.
        Thorax. 1997; 52: s1-s24
        • Miller A.C.
        A fresh look at D-dimer in suspected pulmonary embolism.
        Thorax. 1998; 53: 821-822
        • Boggess K.A.
        • Easterling T.R.
        • Raghu G.
        Management and outcome of pregnant women with interstitial and restrictive lung disease.
        Am J Obstet Gynaecol. 1995; 173: 1007-1014
        • Selroos O.
        Sarcoid and pregnancy. A review with results of a retrospective survey.
        J Intern Med. 1990; 227: 221-224
        • Riley L.
        Pneumonia and tuberculosis in pregnancy.
        Infectious disease clinics of North America. 1997; 11: 119-133
        • Margoner F.
        • Mroveh J.
        • Garely A.
        Research in active tuberculosis amongst pregnant women.
        Obstet Gynaecol. 1994; 83: 911
        • Joint Tuberculous Committee of the British Thoracic Society
        Chemotherapy and management of the tuberculosis in the United Kingdom: recommendations 1998.
        Thorax. 1998; 53: 536-548